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cca [2017-04-24 15:34:12]
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cca [2017-04-24 15:34:12]

tRNA nucleotidyltransferase, maturation of the single-copy tRNACys, which lacks an encoded CCA 3 end
Locus
BSU22450
Isoelectric point
8.04
Molecular weight
45.29 kDa
Protein length
397 aa Sequence Blast
Gene length
1191 bp Sequence Blast
Function
tRNA modification
Product
tRNA nucleotidyltransferase
Essential
yes
E.C.
2.7.7.25
Synonyms
papS, ypjI
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → tRNA modification and maturation
  • Groups of genes → Essential genes

    • This gene is a member of the following regulons

  • Spx regulon

    • Gene

    Coordinates
    2,355,880 → 2,357,073

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • ATP + tRNA(n) = diphosphate + tRNA(n+1) (according to Swiss-Prot)

    • Protein family

  • the protein is similar to the E. coli poly(A) polymerase

    • Structure

  • 1MIV (Geobacillus stearothermophilus 44% identity)

    • Expression and Regulation

    Operons

    Genes
    ypjD-dapB-mgsA-bshB1-bshA-cca-birA
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • Spx: activation, PubMed, in Spx regulon

    • Regulation

  • induced by diamide stess (thiol depletion) (Spx) PubMed
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    References

    Reviews

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    Original publications

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    Operon and expression

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